Acquired hemophilia occurs when the immune system spontaneously develops an antibody, or inhibitor, against its own coagulation factor, frequently factor VIII (FVIII).1
Learn to spot the signs of acquired hemophilia.
Patients with acquired hemophilia may have no personal or family history of bleeding.1 It is critical that urgent lab tests are performed when unexplained bleeding occurs in patients with no bleeding history.
What is acquired hemophilia?

Acquired hemophilia is:


Acquired Hemophilia Video
See how hematologists and emergency medicine physicians respond when a patient presents with unexplained bleeding.
Diagnosis time matters.
Knowing how to spot the signs and symptoms of acquired hemophilia is vital, so that critical laboratory tests can be performed and a diagnosis can be made.
- 35% of patients go undiagnosed for more than 7 days3
- 70% of patients experience severe or life-threatening bleeding3

What makes acquired hemophilia difficult to diagnose?
Because it’s so rare, many ER physicians, oncologists, obstetricians, geriatricians, and other health care providers may not be accustomed to seeing acquired hemophilia.
Patients present with a wide variety of underlying conditions3

Adapted with permission from Knoebl et al.3
Over half of cases are idiopathic.
Adapted with permission from Knoebl et al.3
Over half of cases are idiopathic.
Age and sex distribution of patients with acquired hemophilia3

Adapted from Knoebl et al.3
Adapted from Knoebl et al.3
A bimodal age distribution is associated with acquired hemophilia.

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