What are the signs of acquired hemophilia?
Learn to spot the signs of acquired hemophilia.
Patients with acquired hemophilia have no personal or family history of bleeding.1 It is critical that urgent lab tests are performed when unexplained bleeding occurs in patients with no bleeding history.
Isolated prolonged activated partial thromboplastin time (aPTT)2
Bleeding sites atypical of congenital hemophilia3
Purpura (bruising) and soft-tissue hemorrhage2
Gastrointestinal, urological, or retroperitoneal bleeding1,4
Prolonged bleeding following surgery2
Compartment syndrome (compression of blood vessels and nerves)1,5
How do patients with acquired hemophilia generally present?
Early diagnosis may save lives.6,7
aPTT=activated partial thromboplastin time; PT=prothrombin time.
Algorithm for the diagnosis and management of acquired hemophilia.3
Adapted from Collins et al.3